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Influence of FGF-b, hNGF and hEGF on metabolites level and IgA1- IgA2m1 stable cell lines productivity on 10 days of static culture.

Journal: Journal of Genetic Engineering & Biotechnology

Article Title: Influence of growth factors and different supplements on metabolic response and productivity of IgA-producing CHO cell lines

doi: 10.1016/j.jgeb.2025.100588

Figure Lengend Snippet: Influence of FGF-b, hNGF and hEGF on metabolites level and IgA1- IgA2m1 stable cell lines productivity on 10 days of static culture.

Article Snippet: The medium was supplemented with growth factors such as recombinant human epidermal growth factor (EGF), recombinant human nerve growth factor (β-NGF), and recombinant human fibroblast growth factor (FGF-b) (all Sino Biological, China) as growth stimulants. hFGF-b solution was introduced to final concentrations of 11 ng/ml and hEGF, hNGF solutions were added to a final concentration of 12.5 and 25 ng/well.

Techniques: Stable Transfection